- In conclusion, HPMC, a multifaceted chemical compound, finds its place in the global trade landscape through the HS code system. This coding system ensures fair and systematic trade practices, enabling efficient movement of goods across borders. Whether you are a manufacturer, importer, or exporter, understanding the HPMC's HS code is paramount for seamless operations and compliance with international trade regulations.
- Understanding Hydroxyethyl Cellulose (HEC) Powder A Versatile Polysaccharide Polymer
- The reaction conditions, including the ratio of reagents, temperature, and time, are carefully controlled to yield HPMC with specific properties tailored to its intended use. After the reactions, the resulting product is washed, dried, and then ground into a fine powder, ready for application. HPMC finds extensive use in the pharmaceutical industry as a binder, disintegrant, and viscosity modifier in tablets and capsules. In construction, it is used as a thickener and water retention agent in mortar and plaster. It also plays a crucial role in the food industry as a food additive, improving texture and stability. Additionally, HPMC is employed in the cosmetic and paint industries due to its film-forming and emulsifying properties. In summary, HPMC, made primarily from cellulose and chemically modified with hydroxypropyl and methyl groups, is a versatile material with a broad spectrum of applications. Its production process, rooted in chemistry, showcases the transformative power of modifying natural substances to meet specific industrial needs.
Data on chronic toxicity and carcinogenicity are available for microcrystalline cellulose (E 460), methyl cellulose (E 461) hydroxypropyl cellulose (E 463), HPMC (E 464) and sodium carboxymethyl cellulose (E 466). Some studies were unfit for evaluation due to methodological shortcomings. In the only relevant study, the dietary administration of even high doses of microcrystalline cellulose (E 460) (30%, 15,000 mg/kg bw) to rats for 72 weeks did not affect survival, feed efficiency or haematology. Apart from some dystrophic calcification in renal tubules, no other relevant lesions were noted and tumour incidence did not differ with that of controls. Several studies were conducted in rats with methyl cellulose (E 461) via feed or drinking water or by gavage at concentrations up to 5% (2,500 mg methyl cellulose/kg bw per day) and for up to 2 years. For all examined parameters, no adverse effects were reported and also the observed tumours did not differ in type and number in treated and control groups. In the only identified study, the daily dosing of male and female rats (0, 1,500, 3,000 or 6,000 mg hydroxypropyl cellulose/kg bw) via gavage for 6 months did not cause adverse effects (including carcinogenicity) apart from a decrease in body weight in high-dosed rats (statistically significant in females only). Apart from a decrease in body weights of high-dosed males, no other significant adverse findings were reported and there was no indication of a carcinogenic effect in rats of either sex dietary exposed to HPMC (E 464) up to 20% (10,000 mg/kg bw per day) for 1 year. Carboxy methylcellulose (E 466) was tested in mice and rats at dosages of 0, 10,000 or 100,000 mg/kg diet (equivalent to 0, 1,500 or 15,000 mg/kg bw per day for mice and to 0, 500 or 5,000 mg/kg bw per day for rats) for up to 104 weeks. Despite the increase in feed intake, a treatment related decrease in body weight was noted at the end of the treatment. Histological examination revealed no intestinal abnormality or evidence of the passage of the additive across the intestinal wall in either species and the tumour incidences were comparable among groups.



hydroxyethyl cellulose hec.
Use of HPMC

(3) Coatings industry: As a thickener, dispersant and stabilizer in the coating industry, it has good solubility in water or organic solvents. As paint remover.



hydroxyethyl cellulose thickening mechanism. Additionally, HEC solutions are temperature-dependent, with higher temperatures leading to a decrease in viscosity due to the weakening of hydrogen bonds between the polymer chains.


HPMC

And I’d love to hear from you if you think you have trouble with HPMC or if there are any particular ingredients that you’d like me to look into next.